I really like this, it has so much character. Especially the look on the face.
Main thing I dislike is the square form made by her torso and skirt. I know you said you were going for a blocky thing, but this to me is too jarring. not saying to make her some freakish curvaceous thing, but a little variability will help a lot, in my opinion.
Other thing is the pose. I think the best pose was the initial one you had. It conveyed a certain character very well, and especially with the backstory about your autistic sister then I think you really hit a vein. This new one looks confused and purposeless. If I had to describe what she was doing I'd say she was hitchhiking, and was guilty for some reason. Either that or the casual listless stance of some sort of hipster.
As for the hair, I like both the fro and both new styles. The fro is more interesting to me, makes the character feel more unique, but I have nothing against either new style, they are both nice.
Keep up the good work, glad to see some more pixels from you.