Thank you for your reply yaomon17 but there has been a problem...
We are using a Macintosh for our Project and the program is only for Windows
Thank you once again From HE.corp
You can't run it in a virtual machine or WINE?
Also I'm surprised no-one has posted 'Cosmigo Pro-motion" yet. I know Helm and Ptoing both use it a lot. Personally, it would get my vote except for the fact it has an overengineered GUI that distracts me from the process of actually drawing; rather like GIMP but a little worse.
Therefore, the tool I usually pixel with is GrafX2, with the use of MyPaint's two pixelling brushes to do the initial thumbnailing.
In addition to the efficiency Ashbad mentioned, I also appreciate its extensibility via Lua scripts -- to illustrate the flexibility of this, have a look at Dawnbringer's suite of scripts:
http://www.pixeljoint.com/forum/forum_posts.asp?TID=12854The only issue I have with GrafX2* is that it doesn't import/export palettes from/to .gpl files, which are becoming the standard among Open Source graphics applications: GIMP originated the format, Inkscape, Krita, Scribus, GPick, and others use it.
* Note the capitalization. "GrafX2" is the correct way to spell the name, "Grafx2" is not.