I think I'll make a script like this for GPick.
Anyway, my comments:
* It's a good idea, and the realtime preview is very handy
* it seems a bit random (in the sense of not being strongly tied to reality) currently. The main factor in this is that your model is not realistic.. I mean, you have options for base hue (that's obviously needed...) and hue shift (which, when unconnected to a physical model of light, is not informative about the result) . I'd like to see a model that has more direct implications in relation to reality. For example,
"Base Color, Shadow Color, Highlight Color, Shadow/Highlight Strength". That would allow you to cooordinate lighting conditions across a set of sprites.
* sometimes it lacks contrast, or contrast levels are uneven across the ramp.. I feel that this is at least partly due to the color model you are using, HSV, which is one of the least consistent across different hues. Using HSL, HCY, or LCH.. any of those would produce more reliable results.