Hey, really like the look of this and your self-improvement program
. I'd like to be more thorough but I'm short on time so quick construction/perspective crit for now:
You mentioned 'feigned' perspective and I think that's an issue here: granted it's a bunch of organic Giger-forms and stuff could be pointing every which way, but your construction feels a little wonky in that we're looking up into the ceiling orifice whereas the dais the monster's on looks to be vanishing to a horizon around that point. Quick example here: I moved it up to where I estimated that ellipse would occur in a level creepy-womb-thing, 'cos it's always good to reinforce a consistent perspective; the extra height is kinda dramatic too!
Lately in PS I've been using the polygon tool with max. indented sides to get quick neat guidelines (tiny down arrow next to the blob icon for the options menu there).