Here's another edit, with a few points:

Main problem holding you back is readability of the forms. You seem to have a good grip on the colors and the sort of style you want, the rest is a balancing act of priority.

The doors are a pathway into another room, so they should pop out to the extent that it seems intuitive to go toward it. The floors should be less contrasty because you need to be able to establish a flat plane and easily see the sprites that would be walking across it. Walls can be brought out a bit to show the structural planes of the building and lighten up a bit. I would reiterate the point about the reflection of the windows as well. Remember that bounce light can never be as strong as the light source that it's coming from.

I like what you have, and want to see you push it further. Good luck.

Cool, been streamin some stuff in google hangout, as a branch of Level Up group from FB. Kinda different from digital art, so maybe this is a better audience for it.
http://www.fusroda.com/hangout

Here is a paintover with some suggestions:

-The dither bg doesn't do much for you. Made it all black for cooler contrast.
-Composition: Your version had elizabeth super small and in the top right corner. Moved her and made her bigger so you have more res to render and so the portraits roughly create a triangle. The monster is at the top of the triangle suggesting power.
-The title itself is really sinking into the bg. Make it pop out! Changed the color for readability but you can probably stylize the text more. Don't be afraid to cheat and use a real font. Typeface can really convey emotion if you know which ones to use.
-I flipped victor because I thought it would be more interesting if he's side eying his own creation instead of looking offscreen.
-Anchored the composition with a circle just to make it more obvious who the real focal point was
- Messed around with rendering on all 3 figures mainly combining clusters to go for more implied "brushstrokes" as some the clusters got redundant and hurt readability a bit.
-The bit of orange is just showing the light source and how it might still work even with the flipped victor.

Overall I think you did a good job conveying the emotions in each face, and the colors are great. Clusters are for the most part good. I would also encourage, but this is up to you, an alternative design to the monster rather than relying on the iconography of the Boris Karloff film. Maybe take a description from the book and use that with other non-related ref to come up with a design we haven't all seen before. Keep going.

You've got a good concept here and good ref. Use them! Notice how much taller the grass is on the roof. (Guessing they don't mow up there). Also the house is red which vibrates against the green and gives nice readable planes. (You can still maintain gloomy atmosphere with desaturated reds.) Def have to differentiate the roof green from the ground level grass because it is causing readability problems.

Also I would say to fake some juice and throw some red accents into the grass as well just to let it vibrate and give it some richness/variation in the color pallet. Trees look good but could use some darker values to help push the volume a bit.

Overall it's a great painterly style and I want to see how this progresses. Good idea for an environment and curious to see how you'll start to render those rocks a bit more. Keep pushing it.

Not really related to the thread directly, but I was thinking. Does anyone know what happened to Eyecraft? He was a cool guy to chat with and a great artist. I'd love to see what he's up to these days if anyone knows.