I feel comfortable with everything on the left broad definition side, less so with the right.
The spectrum shows highly controlled/intentional work in the 'pure' space, with less control as you go further out, but the two sides aren't all that equivalent, to me. I think the left is about lack of refinement, or 'finishedness'. Noise is a common signifier of sketchy work, but the attention to pixel-placement in cure's
Incommunicado piece is obvious – and far greater than much work that fits comfortably in the middle.
The right side is much blurrier (
), and ranges much more than the left. You often see work using partial transparency for water/glass/other elements – here the pixel-perfection is maintained, but new (imo dull, ugly) colours are generated outside of the control of the artist. Another example is Fessler's squirrel mockup, where the gradient is clearly delineated from the pixel art. I'm pretty comfortable with both of these types, it's really about whether the automated bits are unobtrusive. Things get messier for me when elements like glows, gradients, and shadows are integrated more deeply. I'm not a fan of detailed pixel work being disrupted, you often get muddy colours and unwarranted attention drawn to higher-resolution, unnaturally smooth elements.
It really is a case-by-case basis thing for me. I'm willing to be way more accommodating when the artist clearly has great pixel chops and is exploring the boundaries of the medium, than I am with somebody slapping a gradient on something out of laziness.