For tilesets of natural features like grass and water, I prefer to do tilesets focusing on diagonals instead of verticals and horizontals, i.e. every tile is basically a corner tile. This allows for a smaller tileset, and more importantly, its structure encourages organic shapes by making straight lines harder to create. The drawback to this style of tileset is most existing automappers don't work well with it, though it could be managed with one based on Wang tiles.
I also think those single-column tiles are kind of useless in most scenarios, as IMHO they create distracting shapes in the environment. They're useful for small-scale games to depict smaller features, but for a large-scale game where a tile is the size of a person or smaller, they're not needed. They're also nearly straight lines by necessity in smaller tiles, which doesn't look natural for things like grass.