In all the reference shots and paintovers, do you see any noses that have a bottom separation between the nose ridge and nosetril? Also do you see any noses where the nosetril actually doesn't show to some degree? Additionally the problem with the odd middle-of-the-nosetril-line-shadow persists. Sorry to pressure you, but you can do even better if you study reality a bit more. Also looking at the ear, don't even attempt it without studying photos a lot, heh.
What's with the underlight on the bottom of the chin?
Generally the rendering on the face is a bit blobbish, it doesn't betray volumes well, and most of the initial problems with the facial characteristics feeling tacked on and/or different planes persist. I guess my biggest suggestion at this point is to fix the immediate issues here as best you can and then hit a lot of from-reference face studies from many angles, building from primitive geometrics to more refined shapes... you're hiding lack of solid anatomical understanding with rendering right now, I think.