What you`re asking for is the basic knowledge of color theory. There`s a quote "from the Internet",
Don`t let the word `theory` intimidate you. An understanding of the basics of color theory and the color wheel is essential for every artist and can increase the possibilities for your work. Colors are, after all, one of the basic tools of painting.
as I wouldn`t say it better.
So, what`s the color wheel? in which ways colors can be put together? what`s the difference between a hue and a shade? what do these all abstract terms like `saturation` or `contrast` mean? how do they work? and so on. If you`re for explaining `what`, `how` and `why`, it`s okay. Otherwise this topic will fill up with hundreds of identical works, boring and pointless.
The traditional art has much to do with pixels, as the pixels still belong to `the visual arts`, it`s obvious. Go for it! It`s a good way to make your practice more interesting as well.
@Dogmeat: That was a digression, I don`t think I know everything.