The pixel art is pretty strong, I could post anatomy nitpicks but I dunno if there's a point to that. Anyway, all arms too long, ab section abnormally squished, feeling reservations on the legs on the whole.
What I don't get is the theme... everybody draws what they find interesting, of course, but, just... muscle man with four arms, top two gesticulating senslessly (?). I get the feeling there's not much thought that went into the composition. Did this start element by element? Did you draw a muscle man with four arms, then let's say the background and finally a wolf, or did you start with a realized composition in mind? If the former, I guess that's ok, this is the sort of thing you get when you improv compositions, but if the latter, I really don't see what this is supposed to be doing, and I believe there's merit in discussing the composition.
This isn't the type of critique this place is here to provide, I know, but then again Alex, you're not the type of artist that needs pixel art critique much, so we might as well discuss construction and themes and all that?
Edit: a strong point I have to make about your art, Alex is that I feel you're enamoured by muscles and how they work, and that's fine. I have that too. I do tens of studies on an arm or something sometimes, but I think you should reign that in when you're doing composed artwork. I think you should perhaps put clothes on your people, hair, props and accessories that signify their personality and the symbolic quality of what you're doing. I really really dig muscle groups and how they work in unison, but I don't think I'd want my art to be defined by that interest. Just a thought.