You’ve probably heard people from Rochester talk about Wegmans like it’s a religious experience. Honestly, if you aren't from around here, it sounds a little bit culty. But for those of us who regularly pull into the parking lot at Wegmans Hylan Drive Henrietta NY, we know the truth. It isn't just a grocery store. It’s a literal ecosystem.
Located at 650 Hylan Drive, right in the heart of the busy Marketplace area, this specific store—officially known as the Marketplace Wegmans—serves a chaotic, beautiful mix of RIT students, suburban families, and commuters looking for a decent sub before hitting the Thruway.
Why the Hylan Drive Location Matters
Every Wegmans has its own "vibe," and the Hylan Drive spot is the workhorse of the Henrietta retail corridor. While the Pittsford flagship gets all the glory for its sheer scale and "Disneyland of Food" energy, Henrietta is where the real work gets done. It’s large enough to have every specialty item you've ever seen on TikTok, but it's laid out in a way that doesn't feel like you need a GPS to find the eggs.
The store anchors a massive shopping district. You've got the Marketplace Outlets right there, and a million other big-box stores nearby. This makes it the ultimate "one-stop" destination. If you're doing a Saturday run to Target or Best Buy, this is where you end up to grab dinner.
The Marketplace Experience: More Than Milk
Let’s talk about the prepared foods because, let’s be real, that's why most people come here. The Market Café at Hylan Drive is a beast. You’ve got the sushi bar (which is actually good, not just "grocery store good"), the pizza station, and the legendary sub shop.
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If you haven't had a Danny's Favorite sub, have you even lived in Western New York? Basically, it’s a rite of passage.
The hot bar and salad bar are usually packed during the lunch rush. It's funny seeing people in business suits standing next to college kids in pajamas, both piling mac and cheese into cardboard containers. It’s the great equalizer.
Some quick facts about this location:
- Address: 650 Hylan Drive, Rochester, NY 14623
- Phone: (585) 424-7255
- Pharmacy Direct Line: (585) 424-7350
- Store Hours: Usually 6:00 AM to 12:00 AM (though always check for holiday shifts)
Navigating the "Henrietta Traffic"
If you’re planning a trip to Wegmans Hylan Drive Henrietta NY, you need a strategy. The intersection of Hylan and Jefferson is notorious. It's busy. It's loud. And during the holidays? Forget it.
Pro tip: Use the back entrances if you can. Coming in from the side near the Marketplace Mall area often saves you three light cycles of frustration.
Once you're inside, the layout is pretty standard for a "large-format" Wegmans. The produce section hits you first—huge, bright, and usually looking like a movie set. They take their "Food You Feel Good About" banner seriously here. You’ll see local apples from Wayne County and greens that look like they were picked twenty minutes ago.
The Pharmacy and Other Essentials
One thing people often overlook is how efficient the pharmacy at this location is. Dealing with insurance is usually a nightmare, but the staff here handles the high volume of the Henrietta/RIT area surprisingly well.
They also have a robust floral department and a massive beer section. Since we're in 2026, the selection of craft brews and non-alcoholic options has expanded significantly. You can find local Rochester staples like Genesee (of course) alongside high-end imports and weirdly specific micro-brews from the Finger Lakes.
Wegmans Hylan Drive Henrietta NY: Common Questions & Misconceptions
People often confuse this store with the Calkins Road location. Calkins Road is literally just a few miles away, but it feels completely different. Calkins is the "neighborhood" store—quiet, tucked away, very suburban. Hylan Drive is the "hub." It’s where you go when you need high-volume shopping or specialty international ingredients that the smaller stores might skip.
Wait, is it 24 hours?
Nope. Those days are mostly gone. Most Wegmans, including the Hylan Drive location, shifted their hours over the last few years. Usually, they close at midnight and reopen at 6:00 AM. It’s a bummer for the 2:00 AM cereal runs, but that’s the current reality.
Is it more expensive?
Honestly, it depends on how you shop. If you stick to the Wegmans brand (which is top-tier quality), it’s often cheaper than name brands at other stores. But if you start wandering into the "Mediterranean Bar" or the artisanal cheese section, your bill will skyrocket fast. That $15 wedge of truffle gouda is tempting, I get it.
A Note on the New Tech
You might have noticed signs about facial recognition or biometric data in some New York stores lately. As of early 2026, Wegmans has clarified that they use some of this tech specifically for loss prevention and identifying people previously flagged for misconduct. It’s a hot topic in the local news, with some shoppers feeling a bit uneasy and others not caring as long as the checkout lines move fast.
Regardless of where you stand, the Hylan Drive store remains one of the busiest in the region, proving that the convenience still outweighs the "Big Brother" vibes for most people.
How to Get the Most Out of Your Visit
If you want to shop like a pro at the Marketplace location, do these things:
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- Use the App: Seriously. Clip the digital coupons before you walk in. The "Savor" coupons and Shoppers Club discounts actually add up.
- Hit the Bakery Early: The "Ultimate" cookies and the fresh-baked sourdough are best before noon. If you wait until 7:00 PM, the selection gets thin.
- Avoid the 5:00 PM Rush: Between 4:30 and 6:30 PM, this store is a zoo. It’s the "after-work" crowd from all the surrounding offices and the university. If you can go at 9:00 AM on a Tuesday, you’ll have the place to yourself.
- Check the Meals2Go: If you’re in a rush, order your sub or pizza on the app while you're still finishing your grocery loop. It’ll be waiting for you at the pickup counter by the time you've paid for your milk and eggs.
Wegmans Hylan Drive Henrietta NY is a staple for a reason. It’s reliable. It’s clean. And it has that weirdly comforting Rochester smell of rotisserie chicken and expensive coffee.
If you're heading there now, keep an eye on the traffic at the Hylan/Jefferson intersection. Maybe grab a Wegmans-brand sparkling water for the road—the ginger lime one is actually incredible.
Actionable Next Steps
- Download the Wegmans App: Before your next trip to Hylan Drive, create a "digital list." The app will actually sort your groceries by aisle number for this specific store, saving you from zig-zagging back and forth across the 100,000-plus square feet of floor space.
- Sign up for Shoppers Club: If you haven't, you're literally throwing money away. The "Shoppers Club" prices are the actual prices; the "regular" prices are the penalty for not having a phone number on file.
- Try the Scan-and-Go: If you hate waiting in the checkout lines (and the Hylan Drive lines can get long), use the mobile scan-and-go feature. You scan items as you put them in your cart and breeze through a dedicated kiosk at the end. It changes the whole experience.