If you tuned into the NFL Week 10 2025 slate expecting the status quo, you probably walked away with a headache. It was weird. Truly. We saw a game in Berlin go into overtime, a "backup" quarterback in Houston look like an All-Pro, and the Super Bowl favorite Buffalo Bills basically forget how to play football for three hours in Miami.
Honestly, the middle of November is usually when the "real" contenders separate themselves. Instead, Week 10 acted like a giant blender. The top of the AFC and NFC standings got shuffled so hard that the Power Rankings now look like they were generated by a random number generator.
The Chaos in Berlin and the Rise of Jonathan Taylor
The international series usually feels like a bit of a gimmick, but the Atlanta Falcons and Indianapolis Colts game in Germany was arguably the game of the year.
Jonathan Taylor basically carried the entire Colts franchise on his back across the Atlantic. He finished with 244 rushing yards. Read that again. 244. His three touchdowns, including the game-winner in overtime, helped the Colts escape with a 31-25 victory. It was a vintage performance that has officially put him at the front of the MVP conversation.
On the other side, the Falcons looked... fine? Drake London went over 100 yards again, which is his fourth time doing that in five games. But "fine" doesn't win in overtime when a human hurricane named Taylor is hitting the C-gap.
NFL Week 10 2025: The Bills’ Miami Meltdown
What really happened with the Bills? Nobody expected a 30-13 blowout. The Dolphins were supposed to be "rebuilding" or "retooling" or whatever word we’re using for a team that looked dead in the water a month ago.
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Buffalo came into this game fresh off a massive win against the Chiefs. Maybe they were hungover. Maybe they just can't handle the humidity. Whatever it was, Josh Allen threw for 310 yards but the offense felt stuck in second gear.
The real story was the Dolphins’ defense. They held the Bills to just 13 points, forcing Buffalo to fall 1.5 games behind the Patriots in the AFC East. If you’re a Bills fan, you’re worried about the injuries. Losing Dalton Kincaid to a hamstring issue and Landon Jackson to a knee injury in the same game is brutal.
Houston Finds a Hero in Davis Mills
C.J. Stroud was out with a concussion. Most people (myself included) wrote the Texans off against the Jaguars. But Davis Mills decided to remind everyone why he’s still in the league.
He didn't just manage the game; he won it. 292 yards and two passing touchdowns, plus a rushing score in the fourth quarter. It was gritty. The Texans won 36-29, proves they aren't just a "one-man show" centered around Stroud.
Also, can we talk about Danielle Hunter? He basically lived in the backfield. Between him and Calen Bullock’s 50-yard interception return, the Texans' defense is starting to look like a unit that nobody wants to see in January.
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Matthew Stafford is Aging Like Fine Wine
While everyone is obsessed with the young guns like Caleb Williams (who, to be fair, had a wild fourth-quarter comeback against the Giants), Matthew Stafford is quietly putting up historic numbers.
In the Rams' 42-26 beatdown of the San Francisco 49ers, Stafford threw four touchdowns. He now has 20 touchdowns and zero interceptions over his last six games. That is a literal NFL record.
He’s making Davante Adams look like he’s 22 again. Even with Adams leaving the game early with an oblique injury (McVay says he’ll be fine), the Rams’ offense looks unstoppable. They’ve scored 86 points in their last three games.
Why the Standings Still Don't Make Sense
It's tempting to look at the scoreboard and make sweeping declarations. But look at the NFC North.
- The Lions crushed the Commanders 44-22.
- The Bears beat the Giants in a nail-biter.
- The Packers lost a 10-7 "defensive struggle" (that’s code for ugly football) to the Eagles on Monday night.
The Packers are sitting at 5-3-1. Matt LaFleur is fielding questions about his job security because the offense can’t seem to score more than 10 points when it matters. It’s a weird vibe in Green Bay. They traded for Micah Parsons to win now, but they’re currently fighting just to stay in the wild-card hunt.
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The Injury Bug is Real
You can’t talk about this week without mentioning the training room. It’s a graveyard.
Garrett Wilson (Jets) went down with a knee injury.
Jaxson Dart (Giants) suffered a concussion.
Darius Slay (Steelers) is out with a concussion.
Joe Alt (Chargers) is out for the season with a high ankle sprain.
Injuries are the great equalizer in the NFL, and right now, the teams that are winning are the ones with the best depth, not necessarily the most star power. The Patriots, for example, are 8-2 despite Rhamondre Stevenson missing time. They’re just... functional. Sometimes functional is all you need when everyone else is falling apart.
What Most People Get Wrong About the 2025 Season
Everyone wants to talk about the "elite" teams. But Week 10 proved there might not be any.
The Seahawks are 6-2 and look great one week, then lose to Tampa Bay the next. The Chiefs are vulnerable. The Bills are inconsistent.
The real insight here? The middle of the pack is huge. Between the 4-win teams and the 7-win teams, there isn't much daylight. One bad snap, one missed field goal (looking at you, Joshua Karty), and the entire season flips.
Next Steps for Week 11 and Beyond:
- Watch the Waiver Wire: If you’re in a fantasy league, Davis Mills and TreVeyon Henderson are no longer "sleepers." They are essential starts if your QB1 or RB1 is on the injury list.
- Monitor the AFC East: The Patriots are currently in the driver's seat. If Buffalo doesn't get healthy on defense, New England might actually run away with the division title.
- Check the Concussion Protocol: With Stroud, Dart, and Wilson all dealing with head or knee issues, Wednesday's practice reports will be more important than the actual games for predicting Week 11 outcomes.
- Betting Value: Keep an eye on the Rams. As long as Stafford stays healthy, they are covering spreads with ease because oddsmakers still haven't adjusted to just how efficient this offense has become.