Well, this was gonna be just a quick little edit, but I started enjoying myself, and got carried away. Gwehehehegh...

Alright here are the changes I remember making:
First and foremost, cleaned up lines around the chin, as it kinda looked like stubble. \:3
Blued up the dark browns and the black in the eyelashes. Incorporating the two purplish blue shades into the skin was a good idea, but the darker shades after them go to a redish brown, which made them look muddy next to those blues. Also added some red to the blue shadow to make it blend with the skin better. Eyelashes are actually quite a bit lighter from all the blue added.
Removed the perimeter light on the left cheek and emphasized the the reflected light on the right side of the face and shoulder.
Toned down the dithering. Going dither crazy makes the sprite look messy, which was evident by the blue in the neck and the heavy dithering on the shoulder. On skin, it's best to use dithering as a method to buffer between shades, not blend between them.
The left eyelash was angled up as it looked off balance, like it was drooping slightly.
Moved the eyes to the right as her gaze was somewhat ambiguous. The pupil in right eye was moved to the right as well, as it was causing a cross eyed effect. Reflections changed to correlate with the reflected light. Added a horizontal reflection for no reason other than it's cool. Removed blue shading in the eye whites and used skin tones instead.
Darkened lower eyelashes, Added some bags below the eyes with shadows and highlights to make the eyes pop more. Added a color for the tear ducts, probably not necessary.
Lots of anti-aliasing around eyes and eyebrows. Lightened outlines around the scalp. Totally unnecessary, but could be educational.
Reshaped lips to be more smile like, added dimples, added highlight above upper lip, broke up highlights on lower lips to give a textured effect. Added nose stud.
Rounded out the clothing, and added the beginnings of some reflected light to match the lighting on the skin.
Brightened up earrings as they where getting lost in the outline of the ear.
Her Right breast (our left) still seems awkward to me but I am unsure of how to correct that since the base line that I am using the creator specified no altering of the lines.
I'd have to see the base to judge, but the profile looks fine to me. I think the crease in her cleavage extends a bit too far out and to the left, which makes it look overly tapered. Maybe that's the problem.
Yeah, I'd say watch out for your dithering more than anything. The way you're using it now is slightly abusive.