You’re tired of Dax screaming in your ear. We all are. But if you haven't pushed through the final "Los Santos Drug Wars" missions yet, you’re basically leaving a mountain of free high-tier content on the table. Honestly, the last dose missions rewards are probably the most generous handouts Rockstar has given us in years without forcing a massive upfront investment in a business property.
Most players jump into these missions because they want the story to end, but the real payoff isn't the cutscene. It’s the hardware. You aren't just getting a few thousand bucks and a "job well done." You’re getting a supercar that usually costs millions and the final key to making the Acid Lab the most profitable solo business in the game. It’s a grind, sure, but it's a calculated one.
What You Actually Get: The Ocelot Virtue and Beyond
The big one. The trophy. The Ocelot Virtue.
Once you finish the final mission, "BDK," Dax will give you a ring. Don't ignore it. He’ll tell you there’s a gift waiting at a parking garage in Pillbox Hill. That "gift" is the Ocelot Virtue, an all-electric supercar that would normally set you back nearly $3 million on Legendary Motorsport. It’s fast. It’s silent. And most importantly, it’s Imani Tech compatible.
This means you can take it to your Agency workshop and slap on a Missile Lock-on Jammer. In a public lobby full of Mk II Oppressor griefers, that jammer is life insurance. You’re getting a top-tier defensive vehicle for $0. Well, $0 and a lot of spent ammo.
📖 Related: The Dawn of the Brave Story Most Players Miss
But it’s not just about the car.
Completing the missions also unlocks the Equipment Upgrade for the Acid Lab. This is the part people miss. Without this upgrade, your Acid Lab is kind of a hobby. With it? It’s a money printer. You’ll need to have completed 10 Fooligan Jobs (call Dax on your phone) to actually install the upgrade, but the Last Dose missions are the narrative gatekeeper. You also get a decent chunk of RP and cash per mission, usually hovering around the $15,000 to $25,000 range depending on the difficulty and time taken, plus a nice one-time $100,000 bonus for finishing the whole strand.
Breaking Down the Mission Payouts
Let’s be real: the individual mission cash isn’t why you’re here. You can make more doing a single Cayo Perico run. But for a solo player or someone just starting out, the accumulation matters.
- This is an Intervention: You’re defending the Freakshop. It’s chaotic. You get paid, but the real reward is just keeping your business alive.
- Unusual Suspects: You’re hunting down Hippies and Lost MC. Typical GTA stuff.
- FriedMind: This is where it gets weird. You’re infiltrating a pharma company.
- Missing Persons: A rescue mission that feels like a classic GTA heist setup.
- BDK: The finale.
Each of these contributes to your overall career progress. If you're on PS5 or Xbox Series X/S, finishing these is mandatory for the Career Progress rewards, which include exclusive clothing like the FriedMind Polo and even more bonus cash.
👉 See also: Why the Clash of Clans Archer Queen is Still the Most Important Hero in the Game
The Acid Lab Multiplier
You have to understand the Acid Lab's place in the 2026 GTA meta. While everyone is focused on the latest mercenary updates or high-stakes robberies, the Acid Lab remains the king of "passive-ish" income.
The last dose missions rewards essentially finalize your setup. By completing the story, you gain the ability to fully optimize the lab. When fully upgraded—which, again, is only possible after these missions—a full bar of product sells for over $335,000. In a high-demand public lobby? You're looking at over $500,000 for a single delivery bike that is incredibly easy to drive.
It’s the only business where the delivery vehicle is actually good. No slow post-op vans. No vulnerable planes. Just a dirt bike that can jump over mountains.
Hidden Perks and Bragging Rights
There are smaller things, too. Finishing the saga unlocks the "Dr. Is In" outfit and a bunch of psychedelic-themed liveries. Are you going to wear them? Maybe not. But having the option is better than not.
✨ Don't miss: Hogwarts Legacy PS5: Why the Magic Still Holds Up in 2026
More importantly, finishing these missions changes the Freakshop. It becomes a fully functional hub. You get access to the weapon workshop there, which is huge for lower-level players who don't own an Avenger, Mobile Operations Center, or Agency yet. It’s a free spot to upgrade your weapons to Mk II versions. That alone saves you the millions you’d spend on a heavy vehicle just to get a thermal scope on your sniper rifle.
Why Most People Mess Up the Ocelot Virtue Claim
I see this constantly: players finish the missions, wait for the call, and then forget to actually save the car. When you pick up the Ocelot Virtue from the parking garage, you have to drive it into one of your own garages. If you leave it on the street or it gets destroyed before you "claim" it as a personal vehicle, you might have to contact Rockstar Support to get it back. Don't be that person. Drive it straight to your most expensive garage and register it.
Also, remember that the Virtue is an EV. It has insane acceleration but a lower top speed compared to gas-powered supercars. It’s a city car. It’s for weaving through traffic and dodging rockets, not for long-distance highway racing.
Practical Next Steps for Maximum Profit
If you’ve just seen the credits roll on the Last Dose, here is exactly what you should do to capitalize on those rewards:
- Go to Pillbox Hill immediately. Look for the yellow "car" icon on your map. That’s your Ocelot Virtue. Get it, garaged it, and then take it to the Agency for that Missile Lock-on Jammer.
- Check your Fooligan Job count. Call Dax. If you haven't done 10 jobs yet, start grinding them. You can do one every 48 minutes (one in-game day).
- Buy the Acid Lab Equipment Upgrade. It costs $250,000. It sounds like a lot, but it pays for itself in exactly one sell mission. This is the single most important thing you can do with your last dose missions rewards progress.
- Toggle your production. Remember to go into the Acid Lab and "Boost Production" once per real-world day. This speeds up the process significantly.
- Upgrade your weapons. Use the Freakshop’s workbench to get those Mk II Heavy Revolvers and Combat MG. You’re going to need them for the higher-level contract missions.
The Last Dose isn't just a story expansion. It’s a starter kit for becoming a Los Santos millionaire. If you're still sitting on "This is an Intervention" because you don't like Dax's vibe, get over it. The car and the business upgrades are worth the headache.