Does size matter? For instance say I wanted to create something like Secret of Mana for instance is it better to keep most character sprites a uniform size or does it not really matter so long as they are all of a uniform scale? Should all sprites conform to some sort of rule when it comes to sizing (for instance all sprites sizes should be a multiplication of 16, eg 32 x 64 or 64 x 64) or can you have the sizes all over the place so long as they are even numbers?